Blockage of epithelial to mesenchymal transition and upregulation of let 7b are critically involved in ursolic acid induced apoptosis in malignant mesothelioma cell

Malignant pleural mesothelioma (MPN), which is caused by asbestos exposure, is one of aggressive lung tumors. In the present study, we elucidated the anti-tumor mechanism of ursolic acid in malignant mesotheliomas. Ursolic acid significantly exerted cytotoxicity in a time and dose dependent manner i...

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Detalles Bibliográficos
Autores principales: Sohn, Eun Jung, Won, Gunho, Lee, Jihyun, Yoon, Sang Wook, Lee, Ilho, Kim, Hee Jeong, Kim, Sung-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5236005/
https://www.ncbi.nlm.nih.gov/pubmed/28090191
http://dx.doi.org/10.7150/ijbs.13453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5236005/
https://www.ncbi.nlm.nih.gov/pubmed/28090191
http://dx.doi.org/10.7150/ijbs.13453

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