Artemisinins Target GABA(A) Receptor Signaling and Impair α Cell Identity

Type 1 diabetes is characterized by the destruction of pancreatic β cells, and generating new insulin-producing cells from other cell types is a major aim of regenerative medicine. One promising approach is transdifferentiation of developmentally related pancreatic cell types, including glucagon-pro...

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Detalles Bibliográficos
Autores principales: Li, Jin, Casteels, Tamara, Frogne, Thomas, Ingvorsen, Camilla, Honoré, Christian, Courtney, Monica, Huber, Kilian V.M., Schmitner, Nicole, Kimmel, Robin A., Romanov, Roman A., Sturtzel, Caterina, Lardeau, Charles-Hugues, Klughammer, Johanna, Farlik, Matthias, Sdelci, Sara, Vieira, Andhira, Avolio, Fabio, Briand, François, Baburin, Igor, Májek, Peter, Pauler, Florian M., Penz, Thomas, Stukalov, Alexey, Gridling, Manuela, Parapatics, Katja, Barbieux, Charlotte, Berishvili, Ekaterine, Spittler, Andreas, Colinge, Jacques, Bennett, Keiryn L., Hering, Steffen, Sulpice, Thierry, Bock, Christoph, Distel, Martin, Harkany, Tibor, Meyer, Dirk, Superti-Furga, Giulio, Collombat, Patrick, Hecksher-Sørensen, Jacob, Kubicek, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5236063/
https://www.ncbi.nlm.nih.gov/pubmed/27916275
http://dx.doi.org/10.1016/j.cell.2016.11.010

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