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Investigation of spiral-wound membrane modules for the cross-flow nanofiltration of fermentation broth obtained from a pilot plant fermentation reactor for the continuous production of lactic acid
BACKGROUND: The separation performance of seven polymer membranes for the nanofiltration of sodium lactate in fermentation broth was investigated. Each module was introduced into the test stand, and the system curve was obtained by recording the permeate flow velocity at different pump head levels....
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5236076/ https://www.ncbi.nlm.nih.gov/pubmed/28133595 http://dx.doi.org/10.1186/s40643-016-0133-5 |
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author | Laube, Hendrik Schneider, Roland Venus, Joachim |
author_facet | Laube, Hendrik Schneider, Roland Venus, Joachim |
author_sort | Laube, Hendrik |
collection | PubMed |
description | BACKGROUND: The separation performance of seven polymer membranes for the nanofiltration of sodium lactate in fermentation broth was investigated. Each module was introduced into the test stand, and the system curve was obtained by recording the permeate flow velocity at different pump head levels. Performance benchmarks were good permeate quality, as determined by high permeate flow velocity, high sodium lactic concentration, low ion impurity concentration, and low organic impurity concentration. Market research has shown that three companies, DOW (TW30, SW30, NF45), General Electric (DK73, DL73), and Microdyn-Nadir (NP30), distributed spiral-wound membrane modules for cross-flow filtration in a 2.5 by 40-in. module size, suitable for operation in the filtration test stand. RESULTS: The measured permeate flow velocity was found to vary widely between the membranes. At a pump head of 250 m, DK73, NP30, and DL73 generated more than 200, 300, and 400% higher permeate flow velocities, respectively, than TW30 and NF45. A key benchmark, lactate rejection, was also highly dependent upon membrane type. The NP30, NF45, and TW30 membranes showed a decrease in lactate permeate flow velocity of 117, 83, and 348% starting at 205, 250, and 300 m, respectively. CONCLUSIONS: The DL73 had the overall best performance according to the measured fermentation broth and lactic acid permeability. The presented method for the graphical analysis of the membrane performance proofed to be a useful tool for the filtration engineer. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s40643-016-0133-5) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-5236076 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-52360762017-01-25 Investigation of spiral-wound membrane modules for the cross-flow nanofiltration of fermentation broth obtained from a pilot plant fermentation reactor for the continuous production of lactic acid Laube, Hendrik Schneider, Roland Venus, Joachim Bioresour Bioprocess Research BACKGROUND: The separation performance of seven polymer membranes for the nanofiltration of sodium lactate in fermentation broth was investigated. Each module was introduced into the test stand, and the system curve was obtained by recording the permeate flow velocity at different pump head levels. Performance benchmarks were good permeate quality, as determined by high permeate flow velocity, high sodium lactic concentration, low ion impurity concentration, and low organic impurity concentration. Market research has shown that three companies, DOW (TW30, SW30, NF45), General Electric (DK73, DL73), and Microdyn-Nadir (NP30), distributed spiral-wound membrane modules for cross-flow filtration in a 2.5 by 40-in. module size, suitable for operation in the filtration test stand. RESULTS: The measured permeate flow velocity was found to vary widely between the membranes. At a pump head of 250 m, DK73, NP30, and DL73 generated more than 200, 300, and 400% higher permeate flow velocities, respectively, than TW30 and NF45. A key benchmark, lactate rejection, was also highly dependent upon membrane type. The NP30, NF45, and TW30 membranes showed a decrease in lactate permeate flow velocity of 117, 83, and 348% starting at 205, 250, and 300 m, respectively. CONCLUSIONS: The DL73 had the overall best performance according to the measured fermentation broth and lactic acid permeability. The presented method for the graphical analysis of the membrane performance proofed to be a useful tool for the filtration engineer. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s40643-016-0133-5) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2017-01-04 2017 /pmc/articles/PMC5236076/ /pubmed/28133595 http://dx.doi.org/10.1186/s40643-016-0133-5 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Research Laube, Hendrik Schneider, Roland Venus, Joachim Investigation of spiral-wound membrane modules for the cross-flow nanofiltration of fermentation broth obtained from a pilot plant fermentation reactor for the continuous production of lactic acid |
title | Investigation of spiral-wound membrane modules for the cross-flow nanofiltration of fermentation broth obtained from a pilot plant fermentation reactor for the continuous production of lactic acid |
title_full | Investigation of spiral-wound membrane modules for the cross-flow nanofiltration of fermentation broth obtained from a pilot plant fermentation reactor for the continuous production of lactic acid |
title_fullStr | Investigation of spiral-wound membrane modules for the cross-flow nanofiltration of fermentation broth obtained from a pilot plant fermentation reactor for the continuous production of lactic acid |
title_full_unstemmed | Investigation of spiral-wound membrane modules for the cross-flow nanofiltration of fermentation broth obtained from a pilot plant fermentation reactor for the continuous production of lactic acid |
title_short | Investigation of spiral-wound membrane modules for the cross-flow nanofiltration of fermentation broth obtained from a pilot plant fermentation reactor for the continuous production of lactic acid |
title_sort | investigation of spiral-wound membrane modules for the cross-flow nanofiltration of fermentation broth obtained from a pilot plant fermentation reactor for the continuous production of lactic acid |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5236076/ https://www.ncbi.nlm.nih.gov/pubmed/28133595 http://dx.doi.org/10.1186/s40643-016-0133-5 |
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