Cargando…

Immunogenicity and Efficacy of Live L. tarentolae Expressing KMP11-NTGP96-GFP Fusion as a Vaccine Candidate against Experimental Visceral Leishmaniasis Caused by L. infantum

BACKGROUND: The aim of present study was to evaluate the protective efficacy of live recombinant L. tarentolae expressing KMP11-NTGP96-GFP fusion as candidates for live engineered recombinant vaccine against visceral leishmaniasis in BALB/c mice. METHODS: KMP-11 and NT-GP96 genes cloned into the pJE...

Descripción completa

Detalles Bibliográficos
Autores principales:	NASIRI, Vahid, DALIMI, Abdolhossein, GHAFFARIFAR, Fatemeh, BOLHASSANI, Azam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Tehran University of Medical Sciences 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5236091/ https://www.ncbi.nlm.nih.gov/pubmed/28096848

Ejemplares similares

Design, Construction and Immunogenicity Assessment of pEGFP-N1-KMP11-GP96 (Fusion) as a DNA Vaccine Candidate against Leishmania major Infection in BALB/c Mice
por: DALIMI, Abdolhossein, et al.
Publicado: (2020)

Development of Novel Prime-Boost Strategies Based on a Tri-Gene Fusion Recombinant L. tarentolae Vaccine against Experimental Murine Visceral Leishmaniasis
por: Saljoughian, Noushin, et al.
Publicado: (2013)

Molecular Identification and Intra-species Variations among Leishmania infantum Isolated from Human and Canine Visceral Leishmaniasis in Iran
por: DALIMI, Abdolhossein, et al.
Publicado: (2018)

Expression of a rK39 homologue from an Iranian Leishmania infantum isolate in Leishmania tarentolae for serodiagnosis of visceral leishmaniasis
por: Rezaei, Zahra, et al.
Publicado: (2019)

In Vitro Antiparasitic and Apoptotic Effects of Antimony Sulfide Nanoparticles on Leishmania infantum
por: Soflaei, Saied, et al.
Publicado: (2012)

Effects of Sheep and Mouse Urine on the Growth Pattern of Leishmania major Promastigotes
por: Nasiri, Vahid, et al.
Publicado: (2013)

In silico analysis and expression of a new chimeric antigen as a vaccine candidate against cutaneous leishmaniasis
por: Motamedpour, Leila, et al.
Publicado: (2020)

The immunogenicity and protective immunity of multi-epitopes DNA prime-protein boost vaccines encoding Amastin-Kmp-11, Kmp11-Gp63 and Amastin-Gp63 against visceral leishmaniasis
por: Zhang, Jianhui, et al.
Publicado: (2020)

Development of a Multi-Epitope Recombinant Protein for the Diagnosis of Human Visceral Leishmaniasis
por: JAMEIE, Farnoosh, et al.
Publicado: (2021)

Leishmania infantum and Human Visceral Leishmaniasis, Argentina
por: Barrio, Alejandra, et al.
Publicado: (2012)

Fatal Visceral Leishmaniasis Caused by Leishmania infantum, Lebanon
por: El Hajj, Rana, et al.
Publicado: (2018)

Investigating in Vivo and in Vitro Effects of Ethanolic and Aqueous Extracts of Myrtle (Myrtus communis) on Leishmania major
por: Hesami, Delshad, et al.
Publicado: (2021)

Characterization of Leishmania (L.) infantum chagasi in visceral leishmaniasis associated with hiv co-infection in Northeastern Brazil
por: de Lima, Elaine Cristina Bomfim, et al.
Publicado: (2017)

Evaluation of synergistic therapeutic effect of shark cartilage extract with artemisinin and glucantime on visceral leishmaniasis in BALB/c mice
por: Molaie, Soheila, et al.
Publicado: (2019)

Molecular Identification of Leishmania infantum kDNA in Naturally Infected Dogs and Their Fleas in an Endemic Focus of Canine Visceral Leishmaniasis in Iran
por: Azarm, Amrollah, et al.
Publicado: (2022)

Visceral leishmaniasis with cutaneous involvement caused by Leishmania infantum-chagasi
por: Raja, Mohammed, et al.
Publicado: (2017)

Pediatric Visceral Leishmaniasis Caused by Leishmania infantum in Northern Cyprus
por: Pasquale, Pagliano, et al.
Publicado: (2017)

Increased levels of cortisol are associated with the severity of experimental visceral leishmaniasis in a Leishmania (L.) infantum-hamster model
por: Barros-Gonçalves, Tayany de D., et al.
Publicado: (2021)

Enhancement of Expression Level of Modified t-PA (TNKase) in Leishmania tarentolae by Induction System
por: Yazdi, Mohammad Mehdi Attarpour, et al.
Publicado: (2019)

Leishmania tarentolae and Leishmania infantum in humans, dogs and cats in the Pelagie archipelago, southern Italy
por: Iatta, Roberta, et al.
Publicado: (2021)

LACK Gene’s Immune Response Induced by Cocktail DNA Vaccine with IL-12 Gene Against Cutaneous Leishmaniasis in BALB/c Mice
por: Jorjani, Oghlniaz, et al.
Publicado: (2018)

Validity and Reliability of Enzyme Immunoassays Using Leishmania major or L. infantum Antigens for the Diagnosis of Canine Visceral Leishmaniasis in Brazil
por: de Arruda, Mauro Maciel, et al.
Publicado: (2013)

Leishmania infantum Induces the Release of sTREM-1 in Visceral Leishmaniasis
por: Bomfim, Lays G. S., et al.
Publicado: (2017)

The Leishmania infantum PUF proteins are targets of the humoral response during visceral leishmaniasis
por: Folgueira, Cristina, et al.
Publicado: (2010)

Detection of Leishmania infantum DNA in the non-parasitized lung of dogs with visceral leishmaniasis
por: Goncalves, Ricardo, et al.
Publicado: (2018)

Use of miltefosine to treat canine visceral leishmaniasis caused by Leishmania infantum in Brazil
por: dos Santos Nogueira, Fabio, et al.
Publicado: (2019)

Western Blot Analysis of Leishmania infantum Antigens in Sera of Patients with Visceral Leishmaniasis
por: HEIDARI, Soudabeh, et al.
Publicado: (2019)

Replacement of Leishmania (Leishmania) infantum Populations in an Endemic Focus of Visceral Leishmaniasis in Brazil
por: Valdivia, Hugo O., et al.
Publicado: (2022)

Enhancement Effect of Shark Cartilage Extract on Treatment of Leishmania infantum with Artemisinin and Glucantime and Evaluation of killing Factors and Apoptosis in-vitro Condition
por: Molaie, Soheila, et al.
Publicado: (2019)

Leishmania (Sauroleishmania) tarentolae isolation and sympatric occurrence with Leishmania (Leishmania) infantum in geckoes, dogs and sand flies
por: Mendoza-Roldan, Jairo Alfonso, et al.
Publicado: (2022)

Assessment of the diagnostic performance of serological tests in areas where Leishmania infantum and Leishmania tarentolae occur in sympatry
por: Iatta, Roberta, et al.
Publicado: (2023)

Mimotope-Based Vaccines of Leishmania infantum Antigens and Their Protective Efficacy against Visceral Leishmaniasis
por: Costa, Lourena Emanuele, et al.
Publicado: (2014)

A Leishmania infantum genetic marker associated with miltefosine treatment failure for visceral leishmaniasis
por: Carnielli, Juliana B.T., et al.
Publicado: (2018)

Anti-Leishmania infantum Antibody-Producing Plasma Cells in the Spleen in Canine Visceral Leishmaniasis
por: Fontes, Jonathan L. M., et al.
Publicado: (2021)

Resistance to Experimental Visceral Leishmaniasis in Mice Infected With Leishmania infantum Requires Batf3
por: Soto, Manuel, et al.
Publicado: (2020)

Genetic variability of Leishmania (Leishmania) infantum causing human visceral leishmaniasis in the Southeastern Brazil
por: Lima, Vinicius Alves, et al.
Publicado: (2023)

Total serum N-glycans mark visceral leishmaniasis in human infections with Leishmania infantum
por: Porcino, Gabriane Nascimento, et al.
Publicado: (2023)

Clinical aspects of visceral leishmaniasis caused by L. infantum in adults. Ten years of experience of the largest outbreak in Europe: what have we learned?
por: Horrillo, Luis, et al.
Publicado: (2019)

In vitro and in vivo antileishmanial effects of aloe-emodin on Leishmania major
por: Dalimi, Abdolhossein, et al.
Publicado: (2015)

In Vitro Study on Cytotoxic Effects of ZnO Nanoparticles on Promastigote and Amastigote Forms of Leishmania major (MRHO/IR/75/ER)
por: DELAVARI, Mahdi, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ui6ad6280lcj40qghug3t5bt47