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Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration
BACKGROUND: Obesity is associated with increased recurrence and reduced survival of breast cancer. Adipocytes constitute a significant component of breast tissue, yet their role in provisioning metabolic substrates to support breast cancer progression is poorly understood. RESULTS: Here, we show tha...
Autores principales: | Balaban, Seher, Shearer, Robert F., Lee, Lisa S., van Geldermalsen, Michelle, Schreuder, Mark, Shtein, Harrison C., Cairns, Rose, Thomas, Kristen C., Fazakerley, Daniel J., Grewal, Thomas, Holst, Jeff, Saunders, Darren N., Hoy, Andrew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237166/ https://www.ncbi.nlm.nih.gov/pubmed/28101337 http://dx.doi.org/10.1186/s40170-016-0163-7 |
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