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Norcantharidin Inhibits cell growth by suppressing the expression and phosphorylation of both EGFR and c-Met in human colon cancer cells

BACKGROUND: Norcantharidin (NCTD) is a Chinese FDA approved, chemically synthesized drug for cancer treatment. The effect of NCTD on signaling proteins of EGFR and c-Met was systematically elucidated in current study. METHODS: Two human colon cancer cell lines, HCT116 and HT29, were used as model sy...

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Detalles Bibliográficos
Autores principales: Qiu, Peiju, Wang, Siwen, Liu, Ming, Ma, He, Zeng, Xuan, Zhang, Meng, Xu, Lingling, Cui, Yidi, Xu, Huixin, Tang, Yang, He, Yanli, Zhang, Lijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237309/
https://www.ncbi.nlm.nih.gov/pubmed/28086832
http://dx.doi.org/10.1186/s12885-016-3039-x