Cargando…
Norcantharidin Inhibits cell growth by suppressing the expression and phosphorylation of both EGFR and c-Met in human colon cancer cells
BACKGROUND: Norcantharidin (NCTD) is a Chinese FDA approved, chemically synthesized drug for cancer treatment. The effect of NCTD on signaling proteins of EGFR and c-Met was systematically elucidated in current study. METHODS: Two human colon cancer cell lines, HCT116 and HT29, were used as model sy...
Autores principales: | Qiu, Peiju, Wang, Siwen, Liu, Ming, Ma, He, Zeng, Xuan, Zhang, Meng, Xu, Lingling, Cui, Yidi, Xu, Huixin, Tang, Yang, He, Yanli, Zhang, Lijuan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237309/ https://www.ncbi.nlm.nih.gov/pubmed/28086832 http://dx.doi.org/10.1186/s12885-016-3039-x |
Ejemplares similares
-
Norcantharidin inhibits proliferation and promotes apoptosis via c‐Met/Akt/mTOR pathway in human osteosarcoma cells
por: Mei, Liangwei, et al.
Publicado: (2019) -
Norcantharidin Induces HL-60 Cells Apoptosis In Vitro
por: Jiang, You-Ming, et al.
Publicado: (2012) -
Norcantharidin, Derivative of Cantharidin, for Cancer Stem Cells
por: Hsieh, Chen-Hsi, et al.
Publicado: (2013) -
Norcantharidin Suppresses Colon Cancer Cell Epithelial-Mesenchymal Transition by Inhibiting the αvβ6-ERK-Ets1 Signaling Pathway
por: Peng, Cheng, et al.
Publicado: (2016) -
Norcantharidin alone or in combination with crizotinib induces autophagic cell death in hepatocellular carcinoma by repressing c-Met-mTOR signaling
por: Sun, Chao-Yue, et al.
Publicado: (2017)