Guidance for the utility of linear models in meta-analysis of genetic association studies of binary phenotypes

Linear mixed models are increasingly used for the analysis of genome-wide association studies (GWAS) of binary phenotypes because they can efficiently and robustly account for population stratification and relatedness through inclusion of random effects for a genetic relationship matrix. However, th...

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Detalles Bibliográficos
Autores principales: Cook, James P, Mahajan, Anubha, Morris, Andrew P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237383/
https://www.ncbi.nlm.nih.gov/pubmed/27848946
http://dx.doi.org/10.1038/ejhg.2016.150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237383/
https://www.ncbi.nlm.nih.gov/pubmed/27848946
http://dx.doi.org/10.1038/ejhg.2016.150

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