The loss-of-function mutations and down-regulated expression of ASB3 gene promote the growth and metastasis of colorectal cancer cells

BACKGROUND: Ankyrin repeat and SOCS box protein 3 (ASB3) is a member of ASB family and contains ankyrin repeat sequence and SOCS box domain. Previous studies indicated that it mediates the ubiquitination and degradation of tumor necrosis factor receptor 2 and is likely involved in inflammatory respo...

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Detalles Bibliográficos
Autores principales: Du, Wu-Ying, Lu, Zhen-Hai, Ye, Wen, Fu, Xiang, Zhou, Yi, Kuang, Chun-Mei, Wu, Jiang-Xue, Pan, Zhi-Zhong, Chen, Shuai, Liu, Ran-Yi, Huang, Wen-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237493/
https://www.ncbi.nlm.nih.gov/pubmed/28088228
http://dx.doi.org/10.1186/s40880-017-0180-0

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