Anti-allodynic effect of Buja in a rat model of oxaliplatin-induced peripheral neuropathy via spinal astrocytes and pro-inflammatory cytokines suppression

BACKGROUND: Oxaliplatin, a widely used anticancer drug against metastatic colorectal cancer, can induce acute peripheral neuropathy, which is characterized by cold and mechanical allodynia. Activation of glial cells (e.g. astrocytes and microglia) and increase of pro-inflammatory cytokines (e.g. IL-...

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Detalles Bibliográficos
Autores principales: Jung, Yongjae, Lee, Ji Hwan, Kim, Woojin, Yoon, Sang Hyub, Kim, Sun Kwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237549/
https://www.ncbi.nlm.nih.gov/pubmed/28088201
http://dx.doi.org/10.1186/s12906-017-1556-z

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