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Insights from molecular modeling, docking and simulation of imidazole nucleus containing chalcones with EGFR kinase domain for improved binding function

EGFR Kinase domain is a crucial role player cell surface receptor protein activated by specific binding of its ligand like EGFR. Importance of this protein as a therapeutically important drug target towards treating various cancer types has been proven elsewhere in previous literature. In this prese...

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Detalles Bibliográficos
Autores principales: Rao, Gondu Eswara, Rahaman, Sk Abdul, Rani, A Prameela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237647/
https://www.ncbi.nlm.nih.gov/pubmed/28104960
http://dx.doi.org/10.6026/97320630012048

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