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Molecular modeling and docking of small molecule inhibitors against NEK2

Aberrant expression of NEK2 (NIMA-related kinase 2) is indicated in a wide variety of human cancers. NEK2 is highly correlated to multi drug resistance by activating drug efflux activity. Identification of new small molecule inhibitors targeted against NEK2 therefore, facilitates to increase drug se...

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Detalles Bibliográficos
Autores principales:	Ramachandran, Balaji, Kesavan, Sabitha, Rajkumar, Thangarajan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Biomedical Informatics 2016
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237649/ https://www.ncbi.nlm.nih.gov/pubmed/28104962 http://dx.doi.org/10.6026/97320630012062

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