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How to unleash mitochondrial apoptotic blockades to kill cancers?
Apoptosis, especially the intrinsic mitochondrial cell death pathway, is regulated by the BCL-2 family of proteins. Defects in apoptotic machinery are one of the main mechanisms that cells employ to evade cell death and become cancerous. Targeting the apoptotic defects, either by direct inhibition o...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237704/ https://www.ncbi.nlm.nih.gov/pubmed/28119805 http://dx.doi.org/10.1016/j.apsb.2016.08.005 |