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Tert-butyl hydroperoxide (t-BHP) induced apoptosis and necroptosis in endothelial cells: Roles of NOX4 and mitochondrion

Oxidative stress causes endothelial death while underlying mechanisms remain elusive. Herein, the pro-death effect of tert-butyl hydroperoxide (t-BHP) was investigated with low concentration (50 μM) of t-BHP (t-BHP(L)) and high concentration (500 μM) of t-BHP (t-BHP(H)). Both t-BHP(L) and t-BHP(H) i...

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Detalles Bibliográficos
Autores principales: Zhao, Wenwen, Feng, Haitao, Sun, Wen, Liu, Kang, Lu, Jin-Jian, Chen, Xiuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237803/
https://www.ncbi.nlm.nih.gov/pubmed/28088644
http://dx.doi.org/10.1016/j.redox.2016.12.036

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