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ATP Binding Cassette Transporter ABCA7 Regulates NKT Cell Development and Function by Controlling CD1d Expression and Lipid Raft Content

ABCA7 is an ABC transporter expressed on the plasma membrane, and actively exports phospholipid complexes from the cytoplasmic to the exocytoplasmic leaflet of membranes. Invariant NKT (iNKT) cells are a subpopulation of T lymphocytes that recognize glycolipid antigens in the context of CD1d-mediate...

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Detalles Bibliográficos
Autores principales:	Nowyhed, Heba N., Chandra, Shilpi, Kiosses, William, Marcovecchio, Paola, Andary, Farah, Zhao, Meng, Fitzgerald, Michael L., Kronenberg, Mitchell, Hedrick, Catherine C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238393/ https://www.ncbi.nlm.nih.gov/pubmed/28091533 http://dx.doi.org/10.1038/srep40273

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