Adjuvant and carrier protein-dependent T-cell priming promotes a robust antibody response against the Plasmodium falciparum Pfs25 vaccine candidate

Humoral immune responses have the potential to maintain protective antibody levels for years due to the immunoglobulin-secreting activity of long-lived plasma cells (LLPCs). However, many subunit vaccines under development fail to generate robust LLPC responses, and therefore a variety of strategies...

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Detalles Bibliográficos
Autores principales: Radtke, Andrea J., Anderson, Charles F., Riteau, Nicolas, Rausch, Kelly, Scaria, Puthupparampil, Kelnhofer, Emily R., Howard, Randall F., Sher, Alan, Germain, Ronald N., Duffy, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238395/
https://www.ncbi.nlm.nih.gov/pubmed/28091576
http://dx.doi.org/10.1038/srep40312

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