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A computational psychiatry approach identifies how alpha-2A noradrenergic agonist Guanfacine affects feature-based reinforcement learning in the macaque

Noradrenaline is believed to support cognitive flexibility through the alpha 2A noradrenergic receptor (a2A-NAR) acting in prefrontal cortex. Enhanced flexibility has been inferred from improved working memory with the a2A-NA agonist Guanfacine. But it has been unclear whether Guanfacine improves sp...

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Detalles Bibliográficos
Autores principales:	Hassani, S. A., Oemisch, M., Balcarras, M., Westendorff, S., Ardid, S., van der Meer, M. A., Tiesinga, P., Womelsdorf, T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238510/ https://www.ncbi.nlm.nih.gov/pubmed/28091572 http://dx.doi.org/10.1038/srep40606

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