Facile synthesis of indolo[3,2-a]carbazoles via Pd-catalyzed twofold oxidative cyclization

A rapid and efficient route has been developed for the synthesis of 9-methoxycarbonylindolo[3,2-a]carbazole derivatives. The key steps in this approach involved an aromatic amination and an oxidative biaryl coupling. Via the present route, indolo[3,2-a]carbazole derivatives are available in 3–4 step...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Chao, Lin, Kai, Huang, Lan, Pan, Wei-dong, Liu, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238593/
https://www.ncbi.nlm.nih.gov/pubmed/28144317
http://dx.doi.org/10.3762/bjoc.12.243
_version_ 1782495732945649664
author Yang, Chao
Lin, Kai
Huang, Lan
Pan, Wei-dong
Liu, Sheng
author_facet Yang, Chao
Lin, Kai
Huang, Lan
Pan, Wei-dong
Liu, Sheng
author_sort Yang, Chao
collection PubMed
description A rapid and efficient route has been developed for the synthesis of 9-methoxycarbonylindolo[3,2-a]carbazole derivatives. The key steps in this approach involved an aromatic amination and an oxidative biaryl coupling. Via the present route, indolo[3,2-a]carbazole derivatives are available in 3–4 steps based on commercially available starting materials.
format Online
Article
Text
id pubmed-5238593
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Beilstein-Institut
record_format MEDLINE/PubMed
spelling pubmed-52385932017-01-31 Facile synthesis of indolo[3,2-a]carbazoles via Pd-catalyzed twofold oxidative cyclization Yang, Chao Lin, Kai Huang, Lan Pan, Wei-dong Liu, Sheng Beilstein J Org Chem Letter A rapid and efficient route has been developed for the synthesis of 9-methoxycarbonylindolo[3,2-a]carbazole derivatives. The key steps in this approach involved an aromatic amination and an oxidative biaryl coupling. Via the present route, indolo[3,2-a]carbazole derivatives are available in 3–4 steps based on commercially available starting materials. Beilstein-Institut 2016-11-22 /pmc/articles/PMC5238593/ /pubmed/28144317 http://dx.doi.org/10.3762/bjoc.12.243 Text en Copyright © 2016, Yang et al. https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Letter
Yang, Chao
Lin, Kai
Huang, Lan
Pan, Wei-dong
Liu, Sheng
Facile synthesis of indolo[3,2-a]carbazoles via Pd-catalyzed twofold oxidative cyclization
title Facile synthesis of indolo[3,2-a]carbazoles via Pd-catalyzed twofold oxidative cyclization
title_full Facile synthesis of indolo[3,2-a]carbazoles via Pd-catalyzed twofold oxidative cyclization
title_fullStr Facile synthesis of indolo[3,2-a]carbazoles via Pd-catalyzed twofold oxidative cyclization
title_full_unstemmed Facile synthesis of indolo[3,2-a]carbazoles via Pd-catalyzed twofold oxidative cyclization
title_short Facile synthesis of indolo[3,2-a]carbazoles via Pd-catalyzed twofold oxidative cyclization
title_sort facile synthesis of indolo[3,2-a]carbazoles via pd-catalyzed twofold oxidative cyclization
topic Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238593/
https://www.ncbi.nlm.nih.gov/pubmed/28144317
http://dx.doi.org/10.3762/bjoc.12.243
work_keys_str_mv AT yangchao facilesynthesisofindolo32acarbazolesviapdcatalyzedtwofoldoxidativecyclization
AT linkai facilesynthesisofindolo32acarbazolesviapdcatalyzedtwofoldoxidativecyclization
AT huanglan facilesynthesisofindolo32acarbazolesviapdcatalyzedtwofoldoxidativecyclization
AT panweidong facilesynthesisofindolo32acarbazolesviapdcatalyzedtwofoldoxidativecyclization
AT liusheng facilesynthesisofindolo32acarbazolesviapdcatalyzedtwofoldoxidativecyclization

Ejemplares similares