Cargando…

Gene therapy for a mouse model of glucose transporter-1 deficiency syndrome

OBJECTIVE: We generated an adeno-associated virus (AAV) vector in which the human SLC2A1 gene was expressed under the synapsin I promoter (AAV-hSLC2A1) and examined if AAV-hSLC2A1 administration can lead to functional improvement in GLUT1-deficient mice. METHODS: AAV-hSLC2A1 was injected into hetero...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nakamura, Sachie, Osaka, Hitoshi, Muramatsu, Shin-ichi, Takino, Naomi, Ito, Mika, Aoki, Shiho, Jimbo, Eriko F., Shimazaki, Kuniko, Onaka, Tatsushi, Ohtsuki, Sumio, Terasaki, Tetsuya, Yamagata, Takanori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238605/ https://www.ncbi.nlm.nih.gov/pubmed/28119822 http://dx.doi.org/10.1016/j.ymgmr.2016.12.008

Ejemplares similares

Gene Therapy in a Mouse Model of Niemann–Pick Disease Type C1
por: Kurokawa, Yoshie, et al.
Publicado: (2021)

Drug screening for Pelizaeus-Merzbacher disease by quantifying the total levels and membrane localization of PLP1
por: Kouga, Takeshi, et al.
Publicado: (2019)

Systemic Delivery of Tyrosine-Mutant AAV Vectors Results in Robust Transduction of Neurons in Adult Mice
por: Iida, Asako, et al.
Publicado: (2013)

WDR45 variants cause ferrous iron loss due to impaired ferritinophagy associated with nuclear receptor coactivator 4 and WD repeat domain phosphoinositide interacting protein 4 reduction
por: Tsukida, Kiwako, et al.
Publicado: (2022)

Engineered adeno-associated virus 3 vector with reduced reactivity to serum antibodies
por: Ito, Mika, et al.
Publicado: (2021)

Probiotics Prevents Sensitization to Oral Antigen and Subsequent Increases in Intestinal Tight Junction Permeability in Juvenile–Young Adult Rats
por: Tulyeu, Janyerkye, et al.
Publicado: (2019)

Attenuation of prostaglandin E(2 )elimination across the mouse blood-brain barrier in lipopolysaccharide-induced inflammation and additive inhibitory effect of cefmetazole
por: Akanuma, Shin-ichi, et al.
Publicado: (2011)

1α,25-Dihydroxyvitamin D(3 )enhances cerebral clearance of human amyloid-β peptide(1-40) from mouse brain across the blood-brain barrier
por: Ito, Shingo, et al.
Publicado: (2011)

Valine metabolites analysis in ECHS1 deficiency
por: Kuwajima, Mari, et al.
Publicado: (2021)

Functional analysis of PAX8 variants identified in patients with congenital hypothyroidism in situ
por: Batjargal, Khishigjargal, et al.
Publicado: (2022)

Total and reduced/oxidized forms of coenzyme Q(10) in fibroblasts of patients with mitochondrial disease
por: Watanabe, Chika, et al.
Publicado: (2023)

A study protocol for quantitative targeted absolute proteomics (QTAP) by LC-MS/MS: application for inter-strain differences in protein expression levels of transporters, receptors, claudin-5, and marker proteins at the blood–brain barrier in ddY, FVB, and C57BL/6J mice
por: Uchida, Yasuo, et al.
Publicado: (2013)

Role of a circadian-relevant gene NR1D1 in brain development: possible involvement in the pathophysiology of autism spectrum disorders
por: Goto, Masahide, et al.
Publicado: (2017)

6q21–22 deletion syndrome with interrupted aortic arch
por: Matsumoto, Ayumi, et al.
Publicado: (2015)

LIN7A Depletion Disrupts Cerebral Cortex Development, Contributing to Intellectual Disability in 12q21-Deletion Syndrome
por: Matsumoto, Ayumi, et al.
Publicado: (2014)

Rescue of amyotrophic lateral sclerosis phenotype in a mouse model by intravenous AAV9-ADAR2 delivery to motor neurons
por: Yamashita, Takenari, et al.
Publicado: (2013)

Wound healing responses of urinary extravasation after urethral injury
por: Hyuga, Taiju, et al.
Publicado: (2023)

Gene therapy improves motor and mental function of aromatic l-amino acid decarboxylase deficiency
por: Kojima, Karin, et al.
Publicado: (2019)

Role of oxytocin in the control of stress and food intake
por: Onaka, Tatsushi, et al.
Publicado: (2019)

Roles of Oxytocin in Stress Responses, Allostasis and Resilience
por: Takayanagi, Yuki, et al.
Publicado: (2021)

The oxytocin system and early‐life experience‐dependent plastic changes
por: Onaka, Tatsushi, et al.
Publicado: (2021)

Reduction in hepatic secondary bile acids caused by short-term antibiotic-induced dysbiosis decreases mouse serum glucose and triglyceride levels
por: Kuno, Takuya, et al.
Publicado: (2018)

Long-term course of early onset developmental and epileptic encephalopathy associated with 2q24.3 microduplication
por: Masuda, Takuya, et al.
Publicado: (2022)

Dopaminergic restoration of prefrontal cortico-putaminal network in gene therapy for aromatic l-amino acid decarboxylase deficiency
por: Onuki, Yoshiyuki, et al.
Publicado: (2021)

Pelizaeus-Merzbacher disease can be a differential diagnosis in males presenting with severe neonatal respiratory distress and hypotonia
por: Ueda, Ayako, et al.
Publicado: (2018)

MCT8 deficiency in a patient with a novel frameshift variant in the SLC16A2 gene
por: Wakabayashi, Kei, et al.
Publicado: (2021)

Intellectual disability and microcephaly associated with a novel CHAMP1 mutation
por: Asakura, Yuta, et al.
Publicado: (2021)

Validation of a newly generated oxytocin antibody for enzyme-linked immunosorbent assays
por: MURATA, Kaori, et al.
Publicado: (2021)

Beneficial Effects of Estrogen in a Mouse Model of Cerebrovascular Insufficiency
por: Kitamura, Naohito, et al.
Publicado: (2009)

Mutation in Parkinson Disease-Associated, G-Protein-Coupled Receptor 37 (GPR37/PaelR) Is Related to Autism Spectrum Disorder
por: Fujita-Jimbo, Eriko, et al.
Publicado: (2012)

The ATRX splicing variant c.21-1G>A is asymptomatic
por: Kojima, Karin, et al.
Publicado: (2022)

Glyceraldehyde caused Alzheimer’s disease-like alterations in diagnostic marker levels in SH-SY5Y human neuroblastoma cells
por: Koriyama, Yoshiki, et al.
Publicado: (2015)

A case of congenital fiber‐type disproportion syndrome presenting dilated cardiomyopathy with ACTA1 mutation
por: Matsumoto, Ayumi, et al.
Publicado: (2022)

The Medial Amygdala-Medullary PrRP-Synthesizing Neuron Pathway Mediates Neuroendocrine Responses to Contextual Conditioned Fear in Male Rodents
por: Yoshida, Masahide, et al.
Publicado: (2014)

Identification of blood biomarkers in glioblastoma by SWATH mass spectrometry and quantitative targeted absolute proteomics
por: Miyauchi, Eisuke, et al.
Publicado: (2018)

Stimulation of Macrophages with the β-Glucan Produced by Aureobasidium pullulans Promotes the Secretion of Tumor Necrosis Factor-Related Apoptosis Inducing Ligand (TRAIL)
por: Kawata, Koji, et al.
Publicado: (2015)

Mitochondrial DNA 3243A>T mutation in a patient with MELAS syndrome
por: Ikeda, Takahiro, et al.
Publicado: (2018)

A TUBB4A Met363Thr variant in pediatric hypomyelination without atrophy of the basal ganglia
por: Hashiguchi, Marina, et al.
Publicado: (2022)

Gelsolin inhibits malignant phenotype of glioblastoma and is regulated by miR‐654‐5p and miR‐450b‐5p
por: Zhang, Jiakang, et al.
Publicado: (2020)

Development of a method for isolating brain capillaries from a single neonatal mouse brain and comparison of proteomic profiles between neonatal and adult brain capillaries
por: Hamada, Yudai, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_sf0titcmcj0gglgcooa4thur7q