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Chitosan-based nanoparticles for improved anticancer efficacy and bioavailability of mifepristone
In addition to its well-known abortifacient effect, mifepristone (MIF) has been used as an anticancer drug for various cancers in many studies with an in-depth understanding of the mechanism of action. However, application of MIF is limited by its poor water solubility and low oral bioavailability....
Autores principales: | Zhang, Huijuan, Wu, Fuqiang, Li, Yazhen, Yang, Xiping, Huang, Jiamei, Lv, Tingting, Zhang, Yingying, Chen, Jianzhong, Chen, Haijun, Gao, Yu, Liu, Guannan, Jia, Lee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238647/ https://www.ncbi.nlm.nih.gov/pubmed/28144535 http://dx.doi.org/10.3762/bjnano.7.178 |
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