Facile fabrication of luminescent organic dots by thermolysis of citric acid in urea melt, and their use for cell staining and polyelectrolyte microcapsule labelling

Luminescent organic dots (O-dots) were synthesized via a one-pot, solvent-free thermolysis of citric acid in urea melt. The influence of the ratio of the precursors and the duration of the process on the properties of the O-dots was established and a mechanism of their formation was hypothesized. Th...

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Detalles Bibliográficos
Autores principales: Zholobak, Nadezhda M, Popov, Anton L, Shcherbakov, Alexander B, Popova, Nelly R, Guzyk, Mykhailo M, Antonovich, Valeriy P, Yegorova, Alla V, Scrypynets, Yuliya V, Leonenko, Inna I, Baranchikov, Alexander Ye, Ivanov, Vladimir K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238650/
https://www.ncbi.nlm.nih.gov/pubmed/28144539
http://dx.doi.org/10.3762/bjnano.7.182
Descripción
Sumario:Luminescent organic dots (O-dots) were synthesized via a one-pot, solvent-free thermolysis of citric acid in urea melt. The influence of the ratio of the precursors and the duration of the process on the properties of the O-dots was established and a mechanism of their formation was hypothesized. The multicolour luminescence tunability and toxicity of synthesized O-dots were extensively studied. The possible applications of O-dots for alive/fixed cell staining and labelling of layer-by-layer polyelectrolyte microcapsules were evaluated.

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