Facile fabrication of luminescent organic dots by thermolysis of citric acid in urea melt, and their use for cell staining and polyelectrolyte microcapsule labelling

Luminescent organic dots (O-dots) were synthesized via a one-pot, solvent-free thermolysis of citric acid in urea melt. The influence of the ratio of the precursors and the duration of the process on the properties of the O-dots was established and a mechanism of their formation was hypothesized. Th...

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Autores principales: Zholobak, Nadezhda M, Popov, Anton L, Shcherbakov, Alexander B, Popova, Nelly R, Guzyk, Mykhailo M, Antonovich, Valeriy P, Yegorova, Alla V, Scrypynets, Yuliya V, Leonenko, Inna I, Baranchikov, Alexander Ye, Ivanov, Vladimir K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238650/
https://www.ncbi.nlm.nih.gov/pubmed/28144539
http://dx.doi.org/10.3762/bjnano.7.182
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author Zholobak, Nadezhda M
Popov, Anton L
Shcherbakov, Alexander B
Popova, Nelly R
Guzyk, Mykhailo M
Antonovich, Valeriy P
Yegorova, Alla V
Scrypynets, Yuliya V
Leonenko, Inna I
Baranchikov, Alexander Ye
Ivanov, Vladimir K
author_facet Zholobak, Nadezhda M
Popov, Anton L
Shcherbakov, Alexander B
Popova, Nelly R
Guzyk, Mykhailo M
Antonovich, Valeriy P
Yegorova, Alla V
Scrypynets, Yuliya V
Leonenko, Inna I
Baranchikov, Alexander Ye
Ivanov, Vladimir K
author_sort Zholobak, Nadezhda M
collection PubMed
description Luminescent organic dots (O-dots) were synthesized via a one-pot, solvent-free thermolysis of citric acid in urea melt. The influence of the ratio of the precursors and the duration of the process on the properties of the O-dots was established and a mechanism of their formation was hypothesized. The multicolour luminescence tunability and toxicity of synthesized O-dots were extensively studied. The possible applications of O-dots for alive/fixed cell staining and labelling of layer-by-layer polyelectrolyte microcapsules were evaluated.
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spelling pubmed-52386502017-01-31 Facile fabrication of luminescent organic dots by thermolysis of citric acid in urea melt, and their use for cell staining and polyelectrolyte microcapsule labelling Zholobak, Nadezhda M Popov, Anton L Shcherbakov, Alexander B Popova, Nelly R Guzyk, Mykhailo M Antonovich, Valeriy P Yegorova, Alla V Scrypynets, Yuliya V Leonenko, Inna I Baranchikov, Alexander Ye Ivanov, Vladimir K Beilstein J Nanotechnol Full Research Paper Luminescent organic dots (O-dots) were synthesized via a one-pot, solvent-free thermolysis of citric acid in urea melt. The influence of the ratio of the precursors and the duration of the process on the properties of the O-dots was established and a mechanism of their formation was hypothesized. The multicolour luminescence tunability and toxicity of synthesized O-dots were extensively studied. The possible applications of O-dots for alive/fixed cell staining and labelling of layer-by-layer polyelectrolyte microcapsules were evaluated. Beilstein-Institut 2016-12-02 /pmc/articles/PMC5238650/ /pubmed/28144539 http://dx.doi.org/10.3762/bjnano.7.182 Text en Copyright © 2016, Zholobak et al. https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjnano/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Nanotechnology terms and conditions: (https://www.beilstein-journals.org/bjnano/terms)
spellingShingle Full Research Paper
Zholobak, Nadezhda M
Popov, Anton L
Shcherbakov, Alexander B
Popova, Nelly R
Guzyk, Mykhailo M
Antonovich, Valeriy P
Yegorova, Alla V
Scrypynets, Yuliya V
Leonenko, Inna I
Baranchikov, Alexander Ye
Ivanov, Vladimir K
Facile fabrication of luminescent organic dots by thermolysis of citric acid in urea melt, and their use for cell staining and polyelectrolyte microcapsule labelling
title Facile fabrication of luminescent organic dots by thermolysis of citric acid in urea melt, and their use for cell staining and polyelectrolyte microcapsule labelling
title_full Facile fabrication of luminescent organic dots by thermolysis of citric acid in urea melt, and their use for cell staining and polyelectrolyte microcapsule labelling
title_fullStr Facile fabrication of luminescent organic dots by thermolysis of citric acid in urea melt, and their use for cell staining and polyelectrolyte microcapsule labelling
title_full_unstemmed Facile fabrication of luminescent organic dots by thermolysis of citric acid in urea melt, and their use for cell staining and polyelectrolyte microcapsule labelling
title_short Facile fabrication of luminescent organic dots by thermolysis of citric acid in urea melt, and their use for cell staining and polyelectrolyte microcapsule labelling
title_sort facile fabrication of luminescent organic dots by thermolysis of citric acid in urea melt, and their use for cell staining and polyelectrolyte microcapsule labelling
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238650/
https://www.ncbi.nlm.nih.gov/pubmed/28144539
http://dx.doi.org/10.3762/bjnano.7.182
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