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Surface-enhanced infrared absorption studies towards a new optical biosensor
Reflectometric interference spectroscopy (RIfS), which is well-established in the visual regime, measures the optical thickness change of a sensitive layer caused, e.g., by binding an analyte. When operated in the mid-infrared range the sensor provides additional information via weak absorption spec...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238651/ https://www.ncbi.nlm.nih.gov/pubmed/28144523 http://dx.doi.org/10.3762/bjnano.7.166 |
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author | Leidner, Lothar Stäb, Julia Adam, Jennifer T Gauglitz, Günter |
author_facet | Leidner, Lothar Stäb, Julia Adam, Jennifer T Gauglitz, Günter |
author_sort | Leidner, Lothar |
collection | PubMed |
description | Reflectometric interference spectroscopy (RIfS), which is well-established in the visual regime, measures the optical thickness change of a sensitive layer caused, e.g., by binding an analyte. When operated in the mid-infrared range the sensor provides additional information via weak absorption spectra (fingerprints). The originally poor spectra are magnified by surface-enhanced infrared absorption (SEIRA). This is demonstrated using the broad complex fluid water band at 3300 cm(−1), which is caused by superposition of symmetric, antisymmetric stretching vibration, and the first overtone of the bending vibration under the influence of H-bonds and Fermi resonance effect. The results are compared with a similar experiment performed with an ATR (attenuated total reflectance) set-up. |
format | Online Article Text |
id | pubmed-5238651 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Beilstein-Institut |
record_format | MEDLINE/PubMed |
spelling | pubmed-52386512017-01-31 Surface-enhanced infrared absorption studies towards a new optical biosensor Leidner, Lothar Stäb, Julia Adam, Jennifer T Gauglitz, Günter Beilstein J Nanotechnol Full Research Paper Reflectometric interference spectroscopy (RIfS), which is well-established in the visual regime, measures the optical thickness change of a sensitive layer caused, e.g., by binding an analyte. When operated in the mid-infrared range the sensor provides additional information via weak absorption spectra (fingerprints). The originally poor spectra are magnified by surface-enhanced infrared absorption (SEIRA). This is demonstrated using the broad complex fluid water band at 3300 cm(−1), which is caused by superposition of symmetric, antisymmetric stretching vibration, and the first overtone of the bending vibration under the influence of H-bonds and Fermi resonance effect. The results are compared with a similar experiment performed with an ATR (attenuated total reflectance) set-up. Beilstein-Institut 2016-11-16 /pmc/articles/PMC5238651/ /pubmed/28144523 http://dx.doi.org/10.3762/bjnano.7.166 Text en Copyright © 2016, Leidner et al. https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjnano/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Nanotechnology terms and conditions: (https://www.beilstein-journals.org/bjnano/terms) |
spellingShingle | Full Research Paper Leidner, Lothar Stäb, Julia Adam, Jennifer T Gauglitz, Günter Surface-enhanced infrared absorption studies towards a new optical biosensor |
title | Surface-enhanced infrared absorption studies towards a new optical biosensor |
title_full | Surface-enhanced infrared absorption studies towards a new optical biosensor |
title_fullStr | Surface-enhanced infrared absorption studies towards a new optical biosensor |
title_full_unstemmed | Surface-enhanced infrared absorption studies towards a new optical biosensor |
title_short | Surface-enhanced infrared absorption studies towards a new optical biosensor |
title_sort | surface-enhanced infrared absorption studies towards a new optical biosensor |
topic | Full Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238651/ https://www.ncbi.nlm.nih.gov/pubmed/28144523 http://dx.doi.org/10.3762/bjnano.7.166 |
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