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Surface-enhanced infrared absorption studies towards a new optical biosensor

Reflectometric interference spectroscopy (RIfS), which is well-established in the visual regime, measures the optical thickness change of a sensitive layer caused, e.g., by binding an analyte. When operated in the mid-infrared range the sensor provides additional information via weak absorption spec...

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Autores principales: Leidner, Lothar, Stäb, Julia, Adam, Jennifer T, Gauglitz, Günter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238651/
https://www.ncbi.nlm.nih.gov/pubmed/28144523
http://dx.doi.org/10.3762/bjnano.7.166
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author Leidner, Lothar
Stäb, Julia
Adam, Jennifer T
Gauglitz, Günter
author_facet Leidner, Lothar
Stäb, Julia
Adam, Jennifer T
Gauglitz, Günter
author_sort Leidner, Lothar
collection PubMed
description Reflectometric interference spectroscopy (RIfS), which is well-established in the visual regime, measures the optical thickness change of a sensitive layer caused, e.g., by binding an analyte. When operated in the mid-infrared range the sensor provides additional information via weak absorption spectra (fingerprints). The originally poor spectra are magnified by surface-enhanced infrared absorption (SEIRA). This is demonstrated using the broad complex fluid water band at 3300 cm(−1), which is caused by superposition of symmetric, antisymmetric stretching vibration, and the first overtone of the bending vibration under the influence of H-bonds and Fermi resonance effect. The results are compared with a similar experiment performed with an ATR (attenuated total reflectance) set-up.
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spelling pubmed-52386512017-01-31 Surface-enhanced infrared absorption studies towards a new optical biosensor Leidner, Lothar Stäb, Julia Adam, Jennifer T Gauglitz, Günter Beilstein J Nanotechnol Full Research Paper Reflectometric interference spectroscopy (RIfS), which is well-established in the visual regime, measures the optical thickness change of a sensitive layer caused, e.g., by binding an analyte. When operated in the mid-infrared range the sensor provides additional information via weak absorption spectra (fingerprints). The originally poor spectra are magnified by surface-enhanced infrared absorption (SEIRA). This is demonstrated using the broad complex fluid water band at 3300 cm(−1), which is caused by superposition of symmetric, antisymmetric stretching vibration, and the first overtone of the bending vibration under the influence of H-bonds and Fermi resonance effect. The results are compared with a similar experiment performed with an ATR (attenuated total reflectance) set-up. Beilstein-Institut 2016-11-16 /pmc/articles/PMC5238651/ /pubmed/28144523 http://dx.doi.org/10.3762/bjnano.7.166 Text en Copyright © 2016, Leidner et al. https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjnano/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Nanotechnology terms and conditions: (https://www.beilstein-journals.org/bjnano/terms)
spellingShingle Full Research Paper
Leidner, Lothar
Stäb, Julia
Adam, Jennifer T
Gauglitz, Günter
Surface-enhanced infrared absorption studies towards a new optical biosensor
title Surface-enhanced infrared absorption studies towards a new optical biosensor
title_full Surface-enhanced infrared absorption studies towards a new optical biosensor
title_fullStr Surface-enhanced infrared absorption studies towards a new optical biosensor
title_full_unstemmed Surface-enhanced infrared absorption studies towards a new optical biosensor
title_short Surface-enhanced infrared absorption studies towards a new optical biosensor
title_sort surface-enhanced infrared absorption studies towards a new optical biosensor
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238651/
https://www.ncbi.nlm.nih.gov/pubmed/28144523
http://dx.doi.org/10.3762/bjnano.7.166
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