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Targeting Argonaute to chromatin

In many eukaryotes, siRNAs bound to Argonaute proteins guide chromatin-modifying enzymes to complementary loci, resulting in transcriptional gene silencing. Multiple lines of evidence indicate that siRNAs base-pair with longer RNAs produced at target loci, but the possibility that siRNAs base-pair d...

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Detalles Bibliográficos
Autores principales: Wendte, Jered M., Pikaard, Craig S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238723/
https://www.ncbi.nlm.nih.gov/pubmed/28087710
http://dx.doi.org/10.1101/gad.294900.116