CD44v6‐Peptide Functionalized Nanoparticles Selectively Bind to Metastatic Cancer Cells

CD44v6 peptide functionalized nanoparticles are fabricated in a facile and controllable way to selectively bind to CD44v6 positive tumor cells with highly efficient anticancer and antimetastatic properties. The reported modular synthesis and facile preparation makes this system highly potent for dev...

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Detalles Bibliográficos
Autores principales: Li, Linxian, Schmitt, Mark, Matzke‐Ogi, Alexandra, Wadhwani, Parvesh, Orian‐Rousseau, Veronique, Levkin, Pavel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238741/
https://www.ncbi.nlm.nih.gov/pubmed/28105395
http://dx.doi.org/10.1002/advs.201600202
Descripción
Sumario:CD44v6 peptide functionalized nanoparticles are fabricated in a facile and controllable way to selectively bind to CD44v6 positive tumor cells with highly efficient anticancer and antimetastatic properties. The reported modular synthesis and facile preparation makes this system highly potent for developing novel multifunctional nanocarriers for therapeutic and/or diagnostic anticancer applications. [Image: see text]

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