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CD44v6‐Peptide Functionalized Nanoparticles Selectively Bind to Metastatic Cancer Cells

CD44v6 peptide functionalized nanoparticles are fabricated in a facile and controllable way to selectively bind to CD44v6 positive tumor cells with highly efficient anticancer and antimetastatic properties. The reported modular synthesis and facile preparation makes this system highly potent for dev...

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Detalles Bibliográficos
Autores principales: Li, Linxian, Schmitt, Mark, Matzke‐Ogi, Alexandra, Wadhwani, Parvesh, Orian‐Rousseau, Veronique, Levkin, Pavel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238741/
https://www.ncbi.nlm.nih.gov/pubmed/28105395
http://dx.doi.org/10.1002/advs.201600202
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author Li, Linxian
Schmitt, Mark
Matzke‐Ogi, Alexandra
Wadhwani, Parvesh
Orian‐Rousseau, Veronique
Levkin, Pavel A.
author_facet Li, Linxian
Schmitt, Mark
Matzke‐Ogi, Alexandra
Wadhwani, Parvesh
Orian‐Rousseau, Veronique
Levkin, Pavel A.
author_sort Li, Linxian
collection PubMed
description CD44v6 peptide functionalized nanoparticles are fabricated in a facile and controllable way to selectively bind to CD44v6 positive tumor cells with highly efficient anticancer and antimetastatic properties. The reported modular synthesis and facile preparation makes this system highly potent for developing novel multifunctional nanocarriers for therapeutic and/or diagnostic anticancer applications. [Image: see text]
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spelling pubmed-52387412017-01-19 CD44v6‐Peptide Functionalized Nanoparticles Selectively Bind to Metastatic Cancer Cells Li, Linxian Schmitt, Mark Matzke‐Ogi, Alexandra Wadhwani, Parvesh Orian‐Rousseau, Veronique Levkin, Pavel A. Adv Sci (Weinh) Communications CD44v6 peptide functionalized nanoparticles are fabricated in a facile and controllable way to selectively bind to CD44v6 positive tumor cells with highly efficient anticancer and antimetastatic properties. The reported modular synthesis and facile preparation makes this system highly potent for developing novel multifunctional nanocarriers for therapeutic and/or diagnostic anticancer applications. [Image: see text] John Wiley and Sons Inc. 2016-12-20 /pmc/articles/PMC5238741/ /pubmed/28105395 http://dx.doi.org/10.1002/advs.201600202 Text en © 2016 The Authors. Published by WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Communications
Li, Linxian
Schmitt, Mark
Matzke‐Ogi, Alexandra
Wadhwani, Parvesh
Orian‐Rousseau, Veronique
Levkin, Pavel A.
CD44v6‐Peptide Functionalized Nanoparticles Selectively Bind to Metastatic Cancer Cells
title CD44v6‐Peptide Functionalized Nanoparticles Selectively Bind to Metastatic Cancer Cells
title_full CD44v6‐Peptide Functionalized Nanoparticles Selectively Bind to Metastatic Cancer Cells
title_fullStr CD44v6‐Peptide Functionalized Nanoparticles Selectively Bind to Metastatic Cancer Cells
title_full_unstemmed CD44v6‐Peptide Functionalized Nanoparticles Selectively Bind to Metastatic Cancer Cells
title_short CD44v6‐Peptide Functionalized Nanoparticles Selectively Bind to Metastatic Cancer Cells
title_sort cd44v6‐peptide functionalized nanoparticles selectively bind to metastatic cancer cells
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238741/
https://www.ncbi.nlm.nih.gov/pubmed/28105395
http://dx.doi.org/10.1002/advs.201600202
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