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Examining whether the information–motivation–behavioral skills model predicts medication adherence for patients with a rare disease

The information–motivation–behavioral skills (IMB) model has been used to explain and promote medication adherence among patients with diabetes and HIV. The objective of this study was to examine whether the IMB model predicted medication adherence among vasculitis patients. Adult vasculitis patient...

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Autores principales: Alexander, Dayna S, Hogan, Susan L, Jordan, Joanne M, DeVellis, Robert F, Carpenter, Delesha M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238767/
https://www.ncbi.nlm.nih.gov/pubmed/28138225
http://dx.doi.org/10.2147/PPA.S115272
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author Alexander, Dayna S
Hogan, Susan L
Jordan, Joanne M
DeVellis, Robert F
Carpenter, Delesha M
author_facet Alexander, Dayna S
Hogan, Susan L
Jordan, Joanne M
DeVellis, Robert F
Carpenter, Delesha M
author_sort Alexander, Dayna S
collection PubMed
description The information–motivation–behavioral skills (IMB) model has been used to explain and promote medication adherence among patients with diabetes and HIV. The objective of this study was to examine whether the IMB model predicted medication adherence among vasculitis patients. Adult vasculitis patients (n=228) completed online questionnaires at baseline and 3-month follow-up. Linear regressions were calculated to determine the direct effects of information and motivation on medication adherence (P<0.05). A mediation analysis using a bootstrapping approach was used to test whether behavioral skills significantly mediated the effect of information and motivation on medication adherence. Participants reported high levels of information (M=4.0; standard deviation [SD]=0.68), moderate levels of motivation (M=2.7; SD=1.00), and high levels of behavioral skills (M=4.1; SD=0.74). In the regression model, only behavioral skills (B=0.38; P<0.001) were significantly associated with medication adherence; however, mediation analysis revealed that behavioral skills significantly mediated the effects of information and motivation on medication adherence. The results support the IMB-hypothesized relationships between information, motivation, behavioral skills, and medication adherence in our sample. Findings suggest that providers should work with vasculitis patients to increase their medication-related skills to improve medication adherence.
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spelling pubmed-52387672017-01-30 Examining whether the information–motivation–behavioral skills model predicts medication adherence for patients with a rare disease Alexander, Dayna S Hogan, Susan L Jordan, Joanne M DeVellis, Robert F Carpenter, Delesha M Patient Prefer Adherence Original Research The information–motivation–behavioral skills (IMB) model has been used to explain and promote medication adherence among patients with diabetes and HIV. The objective of this study was to examine whether the IMB model predicted medication adherence among vasculitis patients. Adult vasculitis patients (n=228) completed online questionnaires at baseline and 3-month follow-up. Linear regressions were calculated to determine the direct effects of information and motivation on medication adherence (P<0.05). A mediation analysis using a bootstrapping approach was used to test whether behavioral skills significantly mediated the effect of information and motivation on medication adherence. Participants reported high levels of information (M=4.0; standard deviation [SD]=0.68), moderate levels of motivation (M=2.7; SD=1.00), and high levels of behavioral skills (M=4.1; SD=0.74). In the regression model, only behavioral skills (B=0.38; P<0.001) were significantly associated with medication adherence; however, mediation analysis revealed that behavioral skills significantly mediated the effects of information and motivation on medication adherence. The results support the IMB-hypothesized relationships between information, motivation, behavioral skills, and medication adherence in our sample. Findings suggest that providers should work with vasculitis patients to increase their medication-related skills to improve medication adherence. Dove Medical Press 2017-01-12 /pmc/articles/PMC5238767/ /pubmed/28138225 http://dx.doi.org/10.2147/PPA.S115272 Text en © 2017 Alexander et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Alexander, Dayna S
Hogan, Susan L
Jordan, Joanne M
DeVellis, Robert F
Carpenter, Delesha M
Examining whether the information–motivation–behavioral skills model predicts medication adherence for patients with a rare disease
title Examining whether the information–motivation–behavioral skills model predicts medication adherence for patients with a rare disease
title_full Examining whether the information–motivation–behavioral skills model predicts medication adherence for patients with a rare disease
title_fullStr Examining whether the information–motivation–behavioral skills model predicts medication adherence for patients with a rare disease
title_full_unstemmed Examining whether the information–motivation–behavioral skills model predicts medication adherence for patients with a rare disease
title_short Examining whether the information–motivation–behavioral skills model predicts medication adherence for patients with a rare disease
title_sort examining whether the information–motivation–behavioral skills model predicts medication adherence for patients with a rare disease
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238767/
https://www.ncbi.nlm.nih.gov/pubmed/28138225
http://dx.doi.org/10.2147/PPA.S115272
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