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Nek2A/SuFu feedback loop regulates Gli-mediated Hedgehog signaling pathway

Suppressor of Fused (SuFu), one of the most conserved components of the Hedgehog (Hh) signaling, binds Gli transcription factors and impedes activation of target gene expression in mammalian cells. Despite the central importance of SuFu in the Hh pathway, little is known about SuFu regulation. In a...

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Detalles Bibliográficos
Autores principales:	Zhou, Fen, Huang, Dengliang, Li, Yong, Hu, Guanghui, Rao, Hai, Lu, Quqin, Luo, Shiwen, Wang, Yao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238777/ https://www.ncbi.nlm.nih.gov/pubmed/28035348 http://dx.doi.org/10.3892/ijo.2016.3819

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