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The protein arginine methyltransferase 5 promotes malignant phenotype of hepatocellular carcinoma cells and is associated with adverse patient outcomes after curative hepatectomy

The prognosis of advanced hepatocellular carcinoma (HCC) is dismal. Novel molecular targets for diagnosis and therapy is urgently required. This study evaluated expression and functions of the protein arginine methyltransferase 5 (PRMT5) in HCC. Using HCC cell lines, the expression levels of PRMT5 m...

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Detalles Bibliográficos
Autores principales:	Shimizu, Dai, Kanda, Mitsuro, Sugimoto, Hiroyuki, Shibata, Masahiro, Tanaka, Haruyoshi, Takami, Hideki, Iwata, Naoki, Hayashi, Masamichi, Tanaka, Chie, Kobayashi, Daisuke, Yamada, Suguru, Nakayama, Goro, Koike, Masahiko, Fujiwara, Michitaka, Fujii, Tsutomu, Kodera, Yasuhiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238779/ https://www.ncbi.nlm.nih.gov/pubmed/28101581 http://dx.doi.org/10.3892/ijo.2017.3833

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