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Partial reconstitution of the RNAi response in human cells using Drosophila gene products

While mammalian somatic cells are incapable of mounting an effective RNA interference (RNAi) response to viral infections, plants and invertebrates are able to generate high levels of viral short interfering RNAs (siRNAs) that can control many infections. In Drosophila, the RNAi response is mediated...

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Detalles Bibliográficos
Autores principales: Kennedy, Edward M., Kornepati, Anand V.R., Bogerd, Hal P., Cullen, Bryan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238790/
https://www.ncbi.nlm.nih.gov/pubmed/27837013
http://dx.doi.org/10.1261/rna.059345.116