Cargando…

Translation initiation by the hepatitis C virus IRES requires eIF1A and ribosomal complex remodeling

Internal ribosome entry sites (IRESs) are important RNA-based translation initiation signals, critical for infection by many pathogenic viruses. The hepatitis C virus (HCV) IRES is the prototype for the type 3 IRESs and is also invaluable for exploring principles of eukaryotic translation initiation...

Descripción completa

Detalles Bibliográficos
Autores principales: Jaafar, Zane A, Oguro, Akihiro, Nakamura, Yoshikazu, Kieft, Jeffrey S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238962/
https://www.ncbi.nlm.nih.gov/pubmed/28009256
http://dx.doi.org/10.7554/eLife.21198