Activation of proinflammatory signaling by 4-hydroxynonenal-Src adducts in aged kidneys

In our previous study, reactive 4-hydroxy-2-nonenal (4-HNE) was shown to activate Src (a non-receptor tyrosine kinase) by forming an adduct on binding with a specific residue of Src, leading to the activation of proinflammatory signaling pathways in cultured cells. However, to date, the deleterious...

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Detalles Bibliográficos
Autores principales: Jang, Eun Ji, Kim, Dae Hyun, Lee, Bonggi, Lee, Eun Kyeong, Chung, Ki Wung, Moon, Kyoung Mi, Kim, Min Jo, An, Hye Jin, Jeong, Ji Won, Kim, Ye Ra, Yu, Byung Pal, Chung, Hae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239442/
https://www.ncbi.nlm.nih.gov/pubmed/27472463
http://dx.doi.org/10.18632/oncotarget.10854

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