A pilot study using dynamic contrast enhanced-MRI as a response biomarker of the radioprotective effect of memantine in patients receiving whole brain radiotherapy

PURPOSE: This pilot prospective study sought to determine whether dynamic contrast enhanced MRI (DCE-MRI) could be used as a clinical imaging biomarker of tissue toxicity from whole brain radiotherapy (WBRT). METHOD: 14 patients who received WBRT were imaged using dynamic contrast enhanced DCE-MRI p...

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Detalles Bibliográficos
Autores principales: Wong, Philip, Leppert, Ilana R., Roberge, David, Boudam, Karim, Brown, Paul D., Muanza, Thierry, Pike, G. Bruce, Chankowsky, Jeffrey, Mihalcioiu, Catalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239453/
https://www.ncbi.nlm.nih.gov/pubmed/27248467
http://dx.doi.org/10.18632/oncotarget.9653

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