Androgen-induced miR-135a acts as a tumor suppressor through downregulating RBAK and MMP11, and mediates resistance to androgen deprivation therapy

The main challenge in the treatment of prostate cancer (PCa) is that the majority of patients inevitably develop resistance to androgen deprivation. However, the mechanisms involved in hormone independent behavior of PCa remain unclear. In the present study, we identified androgen-induced miR-135a a...

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Detalles Bibliográficos
Autores principales: Wan, Xuechao, Pu, Honglei, Huang, Wenhua, Yang, Shu, Zhang, Yalong, Kong, Zhe, Yang, Zhuoran, Zhao, Peiqing, Li, Ao, Li, Tao, Li, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239475/
https://www.ncbi.nlm.nih.gov/pubmed/27323416
http://dx.doi.org/10.18632/oncotarget.9992

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