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Immunotherapy of acute leukemia by chimeric antigen receptor-modified lymphocytes using an improved Sleeping Beauty transposon platform

Chimeric antigen receptor (CAR)-modified T-cell adoptive immunotherapy is a remarkable therapeutic option proven effective in the treatment of hematological malignancies. In order to optimize cell manufacturing, we sought to develop a novel clinical-grade protocol to obtain CAR-modified cytokine-ind...

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Detalles Bibliográficos
Autores principales:	Magnani, Chiara F., Turazzi, Nice, Benedicenti, Fabrizio, Calabria, Andrea, Tenderini, Erika, Tettamanti, Sarah, Attianese, Greta M.P. Giordano, Cooper, Laurence J.N., Aiuti, Alessandro, Montini, Eugenio, Biondi, Andrea, Biagi, Ettore
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239498/ https://www.ncbi.nlm.nih.gov/pubmed/27323395 http://dx.doi.org/10.18632/oncotarget.9955

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