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Establishment and antitumor effects of dasatinib and PKI-587 in BD-138T, a patient-derived muscle invasive bladder cancer preclinical platform with concomitant EGFR amplification and PTEN deletion

Muscle-invasive bladder cancer (MIBC) consists of a heterogeneous group of tumors with a high rate of metastasis and mortality. To facilitate the in-depth investigation and validation of tailored strategies for MIBC treatment, we have developed an integrated approach using advanced high-throughput d...

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Detalles Bibliográficos
Autores principales: Chang, Nakho, Lee, Hye Won, Lim, Joung Eun, Jeong, Da Eun, Song, Hye Jin, Kim, Sudong, Nam, Do-Hyun, Sung, Hyun Hwan, Jeong, Byong Chang, Seo, Seong Il, Jeon, Seong Soo, Lee, Hyun Moo, Choi, Han-Yong, Jeon, Hwang Gyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239502/
https://www.ncbi.nlm.nih.gov/pubmed/27438149
http://dx.doi.org/10.18632/oncotarget.10539