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Epigenetic activation of MGAT3 and corresponding bisecting GlcNAc shortens the survival of cancer patients

Bisecting GlcNAc on N-glycoproteins is described in E-cadherin-, EGF-, Wnt- and integrin- cancer-associated signaling pathways. However, the mechanisms regulating bisecting GlcNAc expression are not clear. Bisecting GlcNAc is attached to N-glycans through beta 1-4 N-acetylglucosaminyl transferase II...

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Detalles Bibliográficos
Autores principales:	Kohler, Reto S., Anugraham, Merrina, López, Mónica Núñez, Xiao, Christina, Schoetzau, Andreas, Hettich, Timm, Schlotterbeck, Goetz, Fedier, André, Jacob, Francis, Heinzelmann-Schwarz, Viola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239506/ https://www.ncbi.nlm.nih.gov/pubmed/27429195 http://dx.doi.org/10.18632/oncotarget.10543

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