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E1A-engineered human umbilical cord mesenchymal stem cells as carriers and amplifiers for adenovirus suppress hepatocarcinoma in mice
Gene therapy is an attractive approach for hepatocellular carcinoma (HCC) patients. Nevertheless, efficient transgene delivery remains a challenge. In this study, we explored a new targeted system based on human umbilical cord-derived mesenchymal stem cells (HUMSCs), which were engineered to deliver...
Autores principales: | Li, Zhenzhen, Ye, Zhou, Zhang, Xiaolong, Zhang, Qing, Fan, Dongmei, Zhang, Yanjun, Luo, Hongbo R., Yuan, Xiangfei, Li, Zongfang, Xiong, Dongsheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239516/ https://www.ncbi.nlm.nih.gov/pubmed/27322080 http://dx.doi.org/10.18632/oncotarget.10122 |
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