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E1A-engineered human umbilical cord mesenchymal stem cells as carriers and amplifiers for adenovirus suppress hepatocarcinoma in mice

Gene therapy is an attractive approach for hepatocellular carcinoma (HCC) patients. Nevertheless, efficient transgene delivery remains a challenge. In this study, we explored a new targeted system based on human umbilical cord-derived mesenchymal stem cells (HUMSCs), which were engineered to deliver...

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Detalles Bibliográficos
Autores principales: Li, Zhenzhen, Ye, Zhou, Zhang, Xiaolong, Zhang, Qing, Fan, Dongmei, Zhang, Yanjun, Luo, Hongbo R., Yuan, Xiangfei, Li, Zongfang, Xiong, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239516/
https://www.ncbi.nlm.nih.gov/pubmed/27322080
http://dx.doi.org/10.18632/oncotarget.10122

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