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Combined genetic and epigenetic interferences with interferon signaling expose prostate cancer cells to viral infection

Interferons (IFNs) induce anti-viral programs, regulate immune responses, and exert anti-proliferative effects. To escape anti-tumorigenic effects of IFNs, malignant cells attenuate JAK/STAT signaling and expression of IFN stimulated genes (ISGs). Such attenuation may enhance the susceptibility of t...

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Detalles Bibliográficos
Autores principales:	Danziger, Oded, Shai, Ben, Sabo, Yosef, Bacharach, Eran, Ehrlich, Marcelo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239539/ https://www.ncbi.nlm.nih.gov/pubmed/27366948 http://dx.doi.org/10.18632/oncotarget.10313

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