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BRILIA: Integrated Tool for High-Throughput Annotation and Lineage Tree Assembly of B-Cell Repertoires

The somatic diversity of antigen-recognizing B-cell receptors (BCRs) arises from Variable (V), Diversity (D), and Joining (J) (VDJ) recombination and somatic hypermutation (SHM) during B-cell development and affinity maturation. The VDJ junction of the BCR heavy chain forms the highly variable compl...

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Detalles Bibliográficos
Autores principales:	Lee, Donald W., Khavrutskii, Ilja V., Wallqvist, Anders, Bavari, Sina, Cooper, Christopher L., Chaudhury, Sidhartha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239784/ https://www.ncbi.nlm.nih.gov/pubmed/28144239 http://dx.doi.org/10.3389/fimmu.2016.00681

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