Next-generation sequencing identifies major DNA methylation changes during progression of Ph+ chronic myeloid leukemia

Little is known about the impact of DNA methylation on the evolution/progression of Ph+ chronic myeloid leukemia (CML). We investigated the methylome of CML patients in chronic phase (CP-CML), accelerated phase (AP-CML) and blast crisis (BC-CML) as well as in controls by reduced representation bisul...

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Detalles Bibliográficos
Autores principales: Heller, G, Topakian, T, Altenberger, C, Cerny-Reiterer, S, Herndlhofer, S, Ziegler, B, Datlinger, P, Byrgazov, K, Bock, C, Mannhalter, C, Hörmann, G, Sperr, W R, Lion, T, Zielinski, C C, Valent, P, Zöchbauer-Müller, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240019/
https://www.ncbi.nlm.nih.gov/pubmed/27211271
http://dx.doi.org/10.1038/leu.2016.143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240019/
https://www.ncbi.nlm.nih.gov/pubmed/27211271
http://dx.doi.org/10.1038/leu.2016.143

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