Interaction of Bacteroides fragilis Toxin with Outer Membrane Vesicles Reveals New Mechanism of Its Secretion and Delivery

The only recognized virulence factor of enterotoxigenic Bacteroides fragilis (ETBF) that accompanies bloodstream infections is the zinc-dependent non-lethal metalloprotease B. fragilis toxin (BFT). The isolated toxin stimulates intestinal secretion, resulting in epithelial damage and necrosis. Numer...

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Detalles Bibliográficos
Autores principales: Zakharzhevskaya, Natalya B., Tsvetkov, Vladimir B., Vanyushkina, Anna A., Varizhuk, Anna M., Rakitina, Daria V., Podgorsky, Victor V., Vishnyakov, Innokentii E., Kharlampieva, Daria D., Manuvera, Valentin A., Lisitsyn, Fedor V., Gushina, Elena A., Lazarev, Vassili N., Govorun, Vadim M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240029/
https://www.ncbi.nlm.nih.gov/pubmed/28144586
http://dx.doi.org/10.3389/fcimb.2017.00002

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