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Urinary Exosomes Contain MicroRNAs Capable of Paracrine Modulation of Tubular Transporters in Kidney

Exosomes derived from all nephron segments are present in human urine, where their functionality is incompletely understood. Most studies have focused on biomarker discovery rather than exosome function. Through sequencing we identified the miRNA repertoire of urinary exosomes from healthy volunteer...

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Detalles Bibliográficos
Autores principales: Gracia, Tannia, Wang, Xiaonan, Su, Ya, Norgett, Elizabeth E., Williams, Timothy L., Moreno, Pablo, Micklem, Gos, Frankl, Fiona E. Karet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240140/
https://www.ncbi.nlm.nih.gov/pubmed/28094285
http://dx.doi.org/10.1038/srep40601