BAFF Index and CXCL13 levels in the cerebrospinal fluid associate respectively with intrathecal IgG synthesis and cortical atrophy in multiple sclerosis at clinical onset

BACKGROUND: B lymphocytes are thought to play a relevant role in multiple sclerosis (MS) pathology. The in vivo analysis of intrathecally produced B cell-related cytokines may help to clarify the mechanisms of B cell recruitment and immunoglobulin production within the central nervous system (CNS) i...

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Detalles Bibliográficos
Autores principales: Puthenparampil, M., Federle, L., Miante, S., Zito, A., Toffanin, E., Ruggero, S., Ermani, M., Pravato, S., Poggiali, D., Perini, P., Rinaldi, F., Gallo, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240243/
https://www.ncbi.nlm.nih.gov/pubmed/28095856
http://dx.doi.org/10.1186/s12974-016-0785-2

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