Radiotherapy and MVA-MUC1-IL-2 vaccine act synergistically for inducing specific immunity to MUC-1 tumor antigen

BACKGROUND: We previously demonstrated that tumor irradiation potentiates cancer vaccines using genetic modification of tumor cells in murine tumor models. To investigate whether tumor irradiation augments the immune response to MUC1 tumor antigen, we have tested the efficacy of tumor irradiation co...

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Detalles Bibliográficos
Autores principales: Hillman, Gilda G., Reich, Lyndsey A., Rothstein, Shoshana E., Abernathy, Lisa M., Fountain, Matthew D., Hankerd, Kali, Yunker, Christopher K., Rakowski, Joseph T., Quemeneur, Eric, Slos, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240430/
https://www.ncbi.nlm.nih.gov/pubmed/28116088
http://dx.doi.org/10.1186/s40425-016-0204-3

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