Cargando…

Efficacy and Safety of Bitopertin in Patients with Schizophrenia and Predominant Negative Symptoms: Subgroup Analysis of Japanese Patients from the Global Randomized Phase 2 Trial

OBJECTIVE: The aim of the present study was to perform a subgroup analysis of data from a phase II global, multi-center, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of bitopertin, a glycine reuptake inhibitor that activates N-methyl-D-aspartate receptors by...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hirayasu, Yoshio, Sato, Shin-Ichi, Shuto, Norifumi, Nakano, Miwa, Higuchi, Teruhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Neuropsychiatric Association 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240458/ https://www.ncbi.nlm.nih.gov/pubmed/28096877 http://dx.doi.org/10.4306/pi.2017.14.1.63

Ejemplares similares

A double-blind randomized study assessing safety and efficacy following one-year adjunctive treatment with bitopertin, a glycine reuptake inhibitor, in Japanese patients with schizophrenia
por: Hirayasu, Yoshio, et al.
Publicado: (2016)

Combining ‘Bottom-Up’ and ‘Top-Down’ Methods to Assess Ethnic Difference in Clearance: Bitopertin as an Example
por: Feng, Sheng, et al.
Publicado: (2015)

The GlyT1 Inhibitor Bitopertin Ameliorates Allodynia and Hyperalgesia in Animal Models of Neuropathic and Inflammatory Pain
por: Armbruster, Anja, et al.
Publicado: (2018)

Criterion and Construct Validity of the CogState Schizophrenia Battery in Japanese Patients with Schizophrenia
por: Yoshida, Taisuke, et al.
Publicado: (2011)

Disentangling the symptoms of schizophrenia: Network analysis in acute phase patients and in patients with predominant negative symptoms
por: Demyttenaere, Koen, et al.
Publicado: (2021)

Case Report: Cariprazine Efficacy in Young Patients Diagnosed With Schizophrenia With Predominantly Negative Symptoms
por: Vasiliu, Octavian
Publicado: (2021)

The Impact of Antipsychotic Treatment on Neurological Soft Signs in Patients with Predominantly Negative Symptoms of Schizophrenia
por: Petrescu, Cristian, et al.
Publicado: (2022)

P1498: INITIAL DATA FROM THE BEACON TRIAL: A PHASE 2, RANDOMIZED, OPEN-LABEL TRIAL OF BITOPERTIN IN ERYTHROPOIETIC PROTOPORPHYRIA
por: Ross, Gayle, et al.
Publicado: (2023)

Long-Term Safety and Efficacy of Blonanserin Transdermal Patches in Japanese Patients with Schizophrenia: A 52-Week Open-Label, Multicenter Study
por: Iwata, Nakao, et al.
Publicado: (2019)

Effectiveness of amisulpride in Chinese patients with predominantly negative symptoms of schizophrenia: a subanalysis of the ESCAPE study
por: Liang, Ying, et al.
Publicado: (2017)

PB2562: STUDY DESIGN OF THE AURORA TRIAL: A PHASE 2, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF BITOPERTIN IN ERYTHROPOIETIC PROTOPORPHYRIA
por: Levy, Cynthia, et al.
Publicado: (2023)

Tau accumulation in the nucleus accumbens in tangle-predominant dementia
por: Kawakami, Ito, et al.
Publicado: (2014)

Long term effects of smoking cessation in hospitalized schizophrenia patients
por: Miyauchi, Masatoshi, et al.
Publicado: (2017)

Depressive Symptoms and PANSS Symptom Dimensions in Patients With Predominant Negative Symptom Schizophrenia: A Network Analysis
por: Demyttenaere, Koen, et al.
Publicado: (2022)

Possible association between Interleukin-1beta gene and schizophrenia in a Japanese population
por: Sasayama, Daimei, et al.
Publicado: (2011)

Efficacy of shared decision making on treatment satisfaction for patients with first-admission schizophrenia: study protocol for a randomised controlled trial
por: Ishii, Mio, et al.
Publicado: (2014)

Lipid‐correlated alterations in the transcriptome are enriched in several specific pathways in the postmortem prefrontal cortex of Japanese patients with schizophrenia
por: Arihisa, Wataru, et al.
Publicado: (2023)

Long-Term Efficacy and Safety of Brexpiprazole in Elderly Japanese Patients with Schizophrenia: A Subgroup Analysis of an Open-Label Study
por: Inada, Ken, et al.
Publicado: (2020)

Japanese experience with milnacipran, the first serotonin and norepinephrine reuptake inhibitor in Japan
por: Higuchi, Teruhiko, et al.
Publicado: (2007)

M184. SOCIAL SKILLS TRAINING FOR TREATMENT-RESISTANT SCHIZOPHRENIA WITH PREDOMINANTLY NEGATIVE SYMPTOMS
por: Kayo, Monica, et al.
Publicado: (2020)

The effect of cariprazine on patient engagement: Post-hoc analysis of a phase 3 study in patients with predominant negative symptoms of schizophrenia
por: Laszlovszky, I., et al.
Publicado: (2021)

Dietary patterns are associated with obesity in Japanese patients with schizophrenia
por: Sugawara, Norio, et al.
Publicado: (2014)

Feasibility and efficacy of shared decision making for first-admission schizophrenia: a randomized clinical trial
por: Ishii, Mio, et al.
Publicado: (2017)

Early-Onset Schizophrenia With Predominantly Negative Symptoms: A Case Study of a Drug-Naive Female Patient Treated With Cariprazine
por: Molnar, Maria Judit, et al.
Publicado: (2020)

PLATELET MAO ACTIVITY IN SUBGROUPS OF SCHIZOPHRENIA
por: Sharma, I., et al.
Publicado: (1990)

Claudin-2 expression is upregulated in the ileum of diarrhea predominant irritable bowel syndrome patients
por: Ishimoto, Haruka, et al.
Publicado: (2017)

Subgroup analysis of Japanese patients in a Phase 3 study of atezolizumab in advanced triple-negative breast cancer (IMpassion130)
por: Iwata, Hiroji, et al.
Publicado: (2019)

Duration Mismatch Negativity Predicts Remission in First-Episode Schizophrenia Patients
por: Nakajima, Suguru, et al.
Publicado: (2021)

Effect of age and disease on bone mass in Japanese patients with schizophrenia
por: Sugawara, Norio, et al.
Publicado: (2012)

The 6-year follow-up of a Japanese patient with silent erythropoietic protoporphyria
por: Mizawa, Megumi, et al.
Publicado: (2017)

Autistic-Like Traits in Adult Patients with Mood Disorders and Schizophrenia
por: Matsuo, Junko, et al.
Publicado: (2015)

Corrigendum to: Subgroup analysis of Japanese patients in a Phase 3 study of atezolizumab in advanced triple-negative breast cancer (IMpassion130)
por: Iwata, Hiroji, et al.
Publicado: (2020)

Predominance of IL-5-secreting drug-specific T cells in subgroups of patients with drug-induced delayed-type hypersensitivity reaction
por: Pfützner, Wolfgang, et al.
Publicado: (2014)

Dose-dependent effect of antipsychotic drugs on autonomic nervous system activity in schizophrenia
por: Iwamoto, Yohko, et al.
Publicado: (2012)

Osteopenia and the physical function in Japanese patients with schizophrenia
por: Uchida, Satoru, et al.
Publicado: (2017)

Palbociclib in combination with letrozole in patients with estrogen receptor–positive, human epidermal growth factor receptor 2–negative advanced breast cancer: PALOMA-2 subgroup analysis of Japanese patients
por: Mukai, Hirofumi, et al.
Publicado: (2018)

Lurasidone in the long-term treatment of Japanese patients with bipolar I disorder: a 52 week open label study
por: Higuchi, Teruhiko, et al.
Publicado: (2021)

Combined Clozapine and Electroconvulsive Therapy in a Japanese Schizophrenia Patient: A Case Report
por: Yoshino, Yuta, et al.
Publicado: (2014)

Clozapine-induced seizures, electroencephalography abnormalities, and clinical responses in Japanese patients with schizophrenia
por: Kikuchi, Yuka Sugawara, et al.
Publicado: (2014)

The Effects of the Combination of Cognitive Training and Supported Employment on Improving Clinical and Working Outcomes for People with Schizophrenia in Japan
por: Sato, Sayaka, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_5o3ck2ll4mh5fi1mkrvh6g7vuk