Current Concepts in Non-Gastrointestinal Stromal Tumor Soft Tissue Sarcomas: A Primer for Radiologists

Non-gastrointestinal stromal tumor (GIST) soft tissue sarcomas (STSs) are a heterogeneous group of neoplasms whose classification and management continues to evolve with better understanding of their biologic behavior. The 2013 World Health Organization (WHO) has revised their classification based o...

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Detalles Bibliográficos
Autores principales: Baheti, Akshay D., Jagannathan, Jyothi P., O'Neill, Ailbhe, Tirumani, Harika, Tirumani, Sree Harsha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Radiology 2017
Materias:
Cancer Imaging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240485/
https://www.ncbi.nlm.nih.gov/pubmed/28096721
http://dx.doi.org/10.3348/kjr.2017.18.1.94
Descripción
Sumario:Non-gastrointestinal stromal tumor (GIST) soft tissue sarcomas (STSs) are a heterogeneous group of neoplasms whose classification and management continues to evolve with better understanding of their biologic behavior. The 2013 World Health Organization (WHO) has revised their classification based on new immunohistochemical and cytogenetic data. In this article, we will provide a brief overview of the revised WHO classification of soft tissue tumors, discuss in detail the radiology and management of the two most common adult non-GIST STS, namely liposarcoma and leiomyosarcoma, and review some of the emerging histology-driven targeted therapies in non-GIST STS, focusing on the role of the radiologist.

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