Cargando…
Plant toxin β-ODAP activates integrin β1 and focal adhesion: A critical pathway to cause neurolathyrism
Neurolathyrism is a unique neurodegeneration disease caused by β-N-oxalyl-L-α, β- diaminopropionic (β-ODAP) present in grass pea seed (Lathyrus stativus L.) and its pathogenetic mechanism is unclear. This issue has become a critical restriction to take full advantage of drought-tolerant grass pea as...
Autores principales: | Tan, Rui-Yue, Xing, Geng-Yan, Zhou, Guang-Ming, Li, Feng-Min, Hu, Wen-Tao, Lambein, Fernand, Xiong, Jun-Lan, Zhang, Sheng-Xiang, Kong, Hai-Yan, Zhu, Hao, Li, Zhi-Xiao, Xiong, You-Cai |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240565/ https://www.ncbi.nlm.nih.gov/pubmed/28094806 http://dx.doi.org/10.1038/srep40677 |
Ejemplares similares
-
Research on Motor Neuron Diseases Konzo and Neurolathyrism: Trends from 1990 to 2010
por: Ngudi, Delphin Diasolua, et al.
Publicado: (2012) -
Proteomic Changes in Chick Brain Proteome Post Treatment with Lathyrus Sativus Neurotoxin, β-N-Oxalyl-L-α,β-Diaminopropionic Acid (L-ODAP): A Better Insight to Transient Neurolathyrism
por: Anil Kumar, D, et al.
Publicado: (2018) -
Identification and characterization of the key enzyme in the biosynthesis of the neurotoxin β-ODAP in grass pea
por: Goldsmith, Moshe, et al.
Publicado: (2022) -
Active and inactive β1 integrins segregate into distinct nanoclusters in focal adhesions
por: Spiess, Matthias, et al.
Publicado: (2018) -
Genomics and biochemical analyses reveal a metabolon key to β-L-ODAP biosynthesis in Lathyrus sativus
por: Edwards, Anne, et al.
Publicado: (2023)