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IL-7 Induces an Epitope Masking of γc Protein in IL-7 Receptor Signaling Complex

IL-7 signaling via IL-7Rα and common γ-chain (γc) is necessary for the development and homeostasis of T cells. Although the delicate mechanism in which IL-7Rα downregulation allows the homeostasis of T cell with limited IL-7 has been well known, the exact mechanism behind the interaction between IL-...

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Detalles Bibliográficos
Autores principales: Goh, Tae Sik, Jo, Yuna, Lee, Byunghyuk, Kim, Geona, Hwang, Hyunju, Ko, Eunhee, Kang, Seung Wan, Oh, Sae-Ock, Baek, Sun-Yong, Yoon, Sik, Lee, Jung Sub, Hong, Changwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240581/
https://www.ncbi.nlm.nih.gov/pubmed/28127156
http://dx.doi.org/10.1155/2017/9096829