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IL-7 Induces an Epitope Masking of γc Protein in IL-7 Receptor Signaling Complex
IL-7 signaling via IL-7Rα and common γ-chain (γc) is necessary for the development and homeostasis of T cells. Although the delicate mechanism in which IL-7Rα downregulation allows the homeostasis of T cell with limited IL-7 has been well known, the exact mechanism behind the interaction between IL-...
Autores principales: | Goh, Tae Sik, Jo, Yuna, Lee, Byunghyuk, Kim, Geona, Hwang, Hyunju, Ko, Eunhee, Kang, Seung Wan, Oh, Sae-Ock, Baek, Sun-Yong, Yoon, Sik, Lee, Jung Sub, Hong, Changwan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240581/ https://www.ncbi.nlm.nih.gov/pubmed/28127156 http://dx.doi.org/10.1155/2017/9096829 |
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